Philadelphia Eagles – How is the health of running back Brian Westbrook (ankle) and should the Eagles bring-in a veteran just in case he is not ready?
Will there be any drop-off in the Eagles defense with Sean McDermott replacing Jim Johnson as defensive coordinator?
With the additions of Jason Peters and the Andrews brothers returning from injury, will the Eagles offensive line be healthy and cohesive for the start of the regular season?
Who is going to replace the lockerroom presence of Tra Thomas, Jon Runyan, and Brian Dawkins?
Will quarterback Donovan McNabb be more consistent in 2009 after a 2008 season where he was too up and down including being benched?
Dallas Cowboys
What affect will the removal of distractions/players Terrell Owens, Pacman Jones, Tank Johnson, SS Roy Williams, defensive coordinator Brian Stewart, and former Romo girlfriend Jessica Simpson have on the team?
Will QB Tony Romo, offensive coordinator Jason Garrett and head coach Wade Phillips survive of being on owner Jerry Jones’ Hot Seat?
Will the 2009 NFL Season produce the Cowboys’ first playoff victory since 1996?
Will Tony Romo continue the trend of producing early (21-8 from September through November over the last two years) and then faltering in December?
Will WR Roy Williams be ready to takeover from T.O as the team’s featured receiver and will he live-up to the high expectations set for him from his 2008 NFL trade deadline deal?
New York Giants
Will it be Domenick Hixon, Steve Smith, Sinorice Moss, Mario Manningham, David Tyree, Hakeem Nicks Ramses Barden, or no one that replaces receiver Plaxico Burress’ production in the Giants offense?
Can Ahmad Bradshaw, Danny Ware, and/or Andre Brown replace departed running back Derrick Ward as Brandon Jacobs' running mate?
Is quarterback Eli Manning ready to be the main leader on the Giants team and is he worth the expected huge contract coming his way?
How will new defensive coordinator Bill Sheridan fair at replacing Steve Spagnuolo (Rams head coach)?
Will DE Osi Umenyiora (knee) and LB Michael Boley (hip) return to full strength by the beginning of the season to help a defense that produced 42 sacks in 2008?
Washington Redskins
Did Redskins owner Daniel Snyder overpay for free agents DT Albert Haynesworth, OL Derrick Dockery and DB DeAngelo Hall?
How will head coach Jim Zorn get along with RB Clinton Portis and will Zorn survive if the Redskins don’t produce in 2009 (i.e. Win a playoff game)?
Can quarterback Jason Campbell rebound from an offseason where the Redskins tried to unsuccessfully obtain Jay Cutler and Mark Sanchez?
How much will the addition of Haynesworth and first-round draft pick Brian Orakpo help improve a defense that usually ranks pretty low in sacks?
Can rookie LB Brian Orakpo make the switch from college defensive end to professional strongside linebacker?
